Classification and application of metal-based nanoantioxidants in medicine and healthcare

• Nguyen Nhat Nam,
• Nguyen Khoi Song Tran,
• Tan Tai Nguyen,
• Nguyen Ngoc Trai,
• Nguyen Phuong Thuy,
• Hoang Dang Khoa Do,
• Nhu Hoa Thi Tran and
• Kieu The Loan Trinh

Beilstein J. Nanotechnol. 2024, 15, 396–415, doi:10.3762/bjnano.15.36

• nanomaterials with more hydroxy groups in the stoichiometric composition generally tend to exhibit higher CAT activity because hydroxy groups enhance ion exchange on the surface of nanomaterials by providing active sites [35][36]. The CAT-like activity was also investigated in copper-based nanomaterials by

Fluorescent bioinspired albumin/polydopamine nanoparticles and their interactions with Escherichia coli cells

• Eloïse Equy,
• Jordana Hirtzel,
• Sophie Hellé,
• Béatrice Heurtault,
• Eric Mathieu,
• Morgane Rabineau,
• Vincent Ball and
• Lydie Ploux

Beilstein J. Nanotechnol. 2023, 14, 1208–1224, doi:10.3762/bjnano.14.100

• KE diad (e.g., catestatin) [13]. During the formation process, hydroxy groups of dopamine form hydrogen bonds with carboxylic groups (COO−) of glutamate (pKa = 4.3), whereas protonated amino groups (NH3+) of lysine (pKa = 10.5) further stabilize the aggregate by cation–π interactions with the

• oxidation (Supporting Information File 1, Figure S2c). This may result from the conjugation and electronic density changes induced during the reaction with H2O2, during which hydroxy groups were oxidized into ketones. Eventually, the large majority of polydopamine functional groups are expected to be

• ketones with only a few remaining of hydroxy groups (Supporting Information File 1, Figure S2a). In addition, labelling of pristine BSA/PDA NPs with FITC and RhBITC dyes led to an obvious change in color of the suspension, from brown (Supporting Information File 1, Figure S3a) to yellow and red

Silver nanoparticles loaded on lactose/alginate: in situ synthesis, catalytic degradation, and pH-dependent antibacterial activity

• Nguyen Thi Thanh Tu,
• T. Lan-Anh Vo,
• T. Thu-Trang Ho,
• Kim-Phuong T. Dang,
• Van-Dung Le,
• Phan Nhat Minh,
• Chi-Hien Dang,
• Vinh-Thien Tran,
• Van-Su Dang,
• Tran Thi Kim Chi,
• Hieu Vu-Quang,
• Radek Fajgar,
• Thi-Lan-Huong Nguyen,
• Van-Dat Doan and
• Thanh-Danh Nguyen

Beilstein J. Nanotechnol. 2023, 14, 781–792, doi:10.3762/bjnano.14.64

• have shown significant improvement in stabilization because of the hydroxy groups in the sugar molecules of the polysaccharide chain, which can form strong associations with AgNPs [13][14][15]. Previous studies have reported that metallic nanoparticles can be easily incorporated into polysaccharides by

Carboxylic acids and light interact to affect nanoceria stability and dissolution in acidic aqueous environments

• Matthew L. Hancock,
• Eric A. Grulke and
• Robert A. Yokel

Beilstein J. Nanotechnol. 2023, 14, 762–780, doi:10.3762/bjnano.14.63

• molecular configurations required for nanoceria complexation. The remaining three acids (glyceric, lactic, and α-hydroxybutyric acid) do not contain a second carboxylic acid group. Furthermore, citric, malic, and isocitric acid molecules all have higher ratios of carboxylic acid and hydroxy groups to

• rate than any other acid in the dark. TEM imaging of nanoceria in citric and β-hydroxybutyric acid supported the DLS results. Relating the carboxylic acid composition (number of carboxylic acid groups, total number of carbons, aliphatic carbons, and hydroxy groups and their molecular ratios) to the

• influence nanoceria agglomeration, the number of carboxylic acid groups and total number of carbons, aliphatic carbons, and hydroxy groups in each carboxylic acid were counted. The molecular ratios of the number of carboxylic acid groups to the total number of carbons and aliphatic carbons, and of the

Humidity-dependent electrical performance of CuO nanowire networks studied by electrochemical impedance spectroscopy

• Jelena Kosmaca,
• Juris Katkevics,
• Jana Andzane,
• Raitis Sondors,
• Liga Jasulaneca,
• Raimonds Meija,
• Kiryl Niherysh,
• Yelyzaveta Rublova and
• Donats Erts

Beilstein J. Nanotechnol. 2023, 14, 683–691, doi:10.3762/bjnano.14.54

• with the adsorbed oxygen and Cu sites on the surface also neutralize holes: [30]. Hence, the impedance can increase with increasing RH (up to about 50% in our system) because of the affected electronic transport inside the material. Simultaneously, as the hydroxy groups begin to form clusters on the

• physisorption of the second layer, that is, H2O molecules forming hydrogen bonds with the hydroxy groups [23][29][32]. This enables the formation of H+ and H3O+ ions, for example, when a proton is transferred from a hydroxy group to a water molecule [33]. A further increase of humidity up to ca. 90% causes the

ZnO-decorated SiC@C hybrids with strong electromagnetic absorption

• Liqun Duan,
• Zhiqian Yang,
• Yilu Xia,
• Xiaoqing Dai,
• Jian’an Wu and
• Minqian Sun

Beilstein J. Nanotechnol. 2023, 14, 565–573, doi:10.3762/bjnano.14.47

• graphene) may be easier because of the abundance of oxygen functional groups (e.g., carboxyl or hydroxy groups) on the carbon surface [26][31][32], in comparison to pure SiC. The introduction of carbon may help to further adjust the electromagnetic parameters and performance of SiC@ZnO nanocomposites

• amorphous state (Figure 2e). The carbon shell may have a positive effect on the nucleation of ZnO particles. This is because oxygen-containing functional groups (such as carboxyl and hydroxy groups) and structural defects are generated on the SiC@C surface during the in situ carbonization [24], which both

• hybrids can be adjusted by changing the dosage of ZnNO3·6H2O. The amorphous carbon shell has a significant effect on the nucleation of crystalline ZnO particles, possibly due to oxygen-containing functional groups (such as carboxyl and hydroxy groups) and defects on the SiC@C surface, which both provide

Single-step extraction of small-diameter single-walled carbon nanotubes in the presence of riboflavin

• Polina M. Kalachikova,
• Anastasia E. Goldt,
• Eldar M. Khabushev,
• Timofei V. Eremin,
• Timofei S. Zatsepin,
• Elena D. Obraztsova,
• Konstantin V. Larionov,
• Liubov Yu. Antipina,
• Pavel B. Sorokin and
• Albert G. Nasibulin

Beilstein J. Nanotechnol. 2022, 13, 1564–1571, doi:10.3762/bjnano.13.130

• SWCNTs occurs due to the adsorption of π-conjugated isoalloxazine moieties on the surface of small-diameter nanotubes and interactions between hydroxy groups of ribityl chains with water. During the SWCNT extraction, specific adsorption of riboflavin to SWCNTs leads to the minimization of interactions

A TiO₂@MWCNTs nanocomposite photoanode for solar-driven water splitting

• Anh Quynh Huu Le,
• Ngoc Nhu Thi Nguyen,
• Hai Duy Tran,
• Van-Huy Nguyen and
• Le-Hai Tran

Beilstein J. Nanotechnol. 2022, 13, 1520–1530, doi:10.3762/bjnano.13.125

• , in which the TiO2 particles are uniformly attached to CNTs by layer-by-layer coating or sol–gel methods [15][16][17]. Notably, the defects on the wall surface of MWCNTs, which enable π–π interactions, could be the active sites to generate the TiO2 agglomerations via hydroxy groups and, thus, enhance

Design of surface nanostructures for chirality sensing based on quartz crystal microbalance

• Yinglin Ma,
• Xiangyun Xiao and
• Qingmin Ji

Beilstein J. Nanotechnol. 2022, 13, 1201–1219, doi:10.3762/bjnano.13.100

• . 1-TNA and 3-MPEA may induce the SA peptide chain to stretch and the aromatic heterocyclic hydrophobic groups of Trp residues and Tyr residues to be exposed, which weaken hydrophobic interactions and strengthen n–π* and π–π* interactions. For 2-OT and MEL cases, their hydroxy groups (−OH) may form

• QCM electrodes for chiral sensing. Cyclodextrin derivatives. Cyclodextrins (CDs) are a class of oligomers composed of glucose units. They possess hollow truncated cones with a lipophilic inner cavity and a hydrophilic edge. The hydroxy groups at the edge can undergo different chemical reactions, which

Application of nanoarchitectonics in moist-electric generation

• Jia-Cheng Feng and
• Hong Xia

Beilstein J. Nanotechnol. 2022, 13, 1185–1200, doi:10.3762/bjnano.13.99

• the fraction of hydroxy groups on the output power. The was a generally positive correlation. However, an excess of hydroxy group content as shown in Figure 7f may affect the stability of the nanostructure and lead to the collapse of the structure. Cellulose materials have great application potential

• voltage to two spiral electrodes, the material between the electrodes generated a gradient of hydroxy groups through polarization. The cathode was reduced to generate more hydroxy groups; the anode was oxidized to generate more o-quinone structures. This asymmetry was demonstrated by the stronger hydrogen

Recent advances in green carbon dots (2015–2022): synthesis, metal ion sensing, and biological applications

• Aisha Kanwal,
• Naheed Bibi,
• Sajjad Hyder,
• Arif Muhammad,
• Hao Ren,
• Jiangtao Liu and
• Zhongli Lei

Beilstein J. Nanotechnol. 2022, 13, 1068–1107, doi:10.3762/bjnano.13.93

• had surface groups such as carboxyl and hydroxy groups. Aloe vera has intrinsic antimicrobial properties, so the bactericidal activity of these CDs was investigated by the agar well diffusion method, and the sensing ability towards Fe3+ was also reported [67]. Kavitha et al. used date palm fronds with

• functional groups such as amino, carboxylate, carbonyl, and hydroxy groups. The cytotoxicity study showed good biocompatibility and applicability in both in vitro and in vivo imaging [116]. Recently, milk was used by Al-Hashimi et al. as a natural precursor to synthesize N-CDs via a solvothermal method

Antibacterial activity of a berberine nanoformulation

• Hue Thi Nguyen,
• Tuyet Nhung Pham,
• Anh-Tuan Le,
• Nguyen Thanh Thuy,
• Tran Quang Huy and
• Thuy Thi Thu Nguyen

Beilstein J. Nanotechnol. 2022, 13, 641–652, doi:10.3762/bjnano.13.56

• solvent that possesses many hydroxy groups. The hydrogen atoms of these hydroxy groups and the oxygen atoms of methoxy and furyl groups of BBR form hydrogen bonds, which can effectively avoid the aggregation of BBR NPs. Therefore, glycerol acts as a stabilizer to improve the distribution and stability of

Stimuli-responsive polypeptide nanogels for trypsin inhibition

• Petr Šálek,
• Jana Dvořáková,
• Sviatoslav Hladysh,
• Diana Oleshchuk,
• Ewa Pavlova,
• Jan Kučka and
• Vladimír Proks

Beilstein J. Nanotechnol. 2022, 13, 538–548, doi:10.3762/bjnano.13.45

• nanogel was not significantly affected by pH change. It was slightly anionic due to excess of carboxyl end groups and hydroxy groups [23]. Negligible difference could be seen between the measurements at 25 °C with an average zeta potential of ca. −7.5 mV and the measurements at 37 °C with an average zeta

Ciprofloxacin-loaded dissolving polymeric microneedles as a potential therapeutic for the treatment of S. aureus skin infections

• Sharif Abdelghany,
• Walhan Alshaer,
• Yazan Al Thaher,
• Maram Al Fawares,
• Amal G. Al-Bakri,
• Saja Zuriekat and
• Randa SH. Mansour

Beilstein J. Nanotechnol. 2022, 13, 517–527, doi:10.3762/bjnano.13.43

• hydroxy groups of PVA and the carbonyl groups of PVP in an intertwined network [43]. Therefore, we assumed that CIP_MN1 composed of PVA/PVP hydrogel had greater mechanical strength than CIP_MN2 composed of PVA and penetrated the Parafilm more efficiently. Overall, the results we obtained signify the

Investigation of a memory effect in a Au/(Ti–Cu)Ox-gradient thin film/TiAlV structure

• Damian Wojcieszak,
• Jarosław Domaradzki,
• Michał Mazur,
• Tomasz Kotwica and
• Danuta Kaczmarek

Beilstein J. Nanotechnol. 2022, 13, 265–273, doi:10.3762/bjnano.13.21

• related to lattice oxygen (for TiO2 and CuO), hydroxy groups (OH−) and adsorbed water molecules (H2Oads). The UPS spectrum of the (Ti0.48Cu0.52)Ox thin film is shown in Figure 7. The position of the valence band maximum (VBM) was determined from the extrapolation of the line fit to the leading edge of the

Engineered titania nanomaterials in advanced clinical applications

• Padmavati Sahare,
• Paulina Govea Alvarez,
• Juan Manual Sanchez Yanez,
• Gabriel Luna-Bárcenas,
• Samik Chakraborty,
• Sujay Paul and
• Miriam Estevez

Beilstein J. Nanotechnol. 2022, 13, 201–218, doi:10.3762/bjnano.13.15

• regarding the hydrophilic or hydrophobic nature of a material as water can percolate more easily inside wider pores than inside smaller pores [22]. Synthesized TiO2 is often covered partially with a layer of hydroxy groups that imparts a negative charge to the surface, making them hydrophilic with a small

• contact angle, which is reported to be favorable for biomedical applications. Likewise, Gatoo et al. proposed that amorphous titania materials are hydrophilic due to the presence of a higher concentration of hydroxy groups upon their surface and the high polarity of the O–Ti–O bond [23]. The surface

• hydroxy groups can react with water molecules. The thus formed hydrogen bonds account for a good wettability. An annealing temperature below 450 °C still retains the hydrophilic behavior because of the combined crystalline phase (anatase and rutile), but above that temperature, the reduction of the number

A comprehensive review on electrospun nanohybrid membranes for wastewater treatment

• Senuri Kumarage,
• Imalka Munaweera and
• Nilwala Kottegoda

Beilstein J. Nanotechnol. 2022, 13, 137–159, doi:10.3762/bjnano.13.10

• metals and other cations, electrospun membranes have been recognized as a promising solution. Most metal ion removing membranes interact with the targeted ions through ionic interactions via functional groups, such as hydroxy groups, carboxyl groups, amino groups, and ester groups, on the membrane

• flexible nanohybrid membrane of Pd NP-decorated polydopamine-SiO2/PVA, which can simultaneously remove organic dyes, chemicals, and oils [83]. (Figure 4 and Figure 5) Superhydrophilicity was found to be a synergistic effect of numerous hydroxy groups from SiO2 NPs and the nano/microscale surface roughness

pH-driven enhancement of anti-tubercular drug loading on iron oxide nanoparticles for drug delivery in macrophages

• Karishma Berta Cotta,
• Sarika Mehra and
• Rajdip Bandyopadhyaya

Beilstein J. Nanotechnol. 2021, 12, 1127–1139, doi:10.3762/bjnano.12.84

• acid with fluorine and a piperazine ring [25]. It exhibits a zwitterionic nature, with a pKa1 and pKa2 of 6.2 and 8.5, respectively [26]. Zwitterionic molecules like amino acids and amphoteric hydroxy groups get adsorbed onto iron oxide nanoparticles predominately via electrostatic interaction [27][28

Silver nanoparticles nucleated in NaOH-treated halloysite: a potential antimicrobial material

• Yuri B. Matos,
• Rodrigo S. Romanus,
• Mattheus Torquato,
• Edgar H. de Souza,
• Rodrigo L. Villanova,
• Marlene Soares and
• Emilson R. Viana

Beilstein J. Nanotechnol. 2021, 12, 798–807, doi:10.3762/bjnano.12.63

• surfaces of HNT have different chemical constitutions, they display different chemical affinities as well. Silver nucleation, for example, is favoured on the aluminol surface, due the high affinity between Ag+ ions and hydroxy groups (OH−) [26]. There is evidence suggesting that the silver nucleation on

• with treatment time. These data indicate that the NaOH chemical bath indeed improves the nucleability of silver on the HNT clay surface. Three mechanisms can be suggested to explain the improved silver nucleation in Ag/HNT-4 and Ag/HNT-8, all of them are related to the fact that hydroxy groups are

• preferential nucleating spots for silver. These mechanisms are: (1) hydroxylation of the HNT surface, that is, by exposing the clay particles to NaOH, hydroxy groups are grafted on the surface [33][34][35], which will later work as nucleating sites for Ag-NPs; (2) corrosion-induced crystalline defects, that is

Impact of GaAs(100) surface preparation on EQE of AZO/Al₂O₃/p-GaAs photovoltaic structures

• Piotr Caban,
• Rafał Pietruszka,
• Jarosław Kaszewski,
• Monika Ożga,
• Bartłomiej S. Witkowski,
• Krzysztof Kopalko,
• Piotr Kuźmiuk,
• Katarzyna Gwóźdź,
• Ewa Płaczek-Popko,
• Krystyna Lawniczak-Jablonska and
• Marek Godlewski

Beilstein J. Nanotechnol. 2021, 12, 578–592, doi:10.3762/bjnano.12.48

• 0.84 to 0.94 [36] and even close to 0.99 according to Baca and Ashby [52]. It is also known that NH4OH surface treatment leaves it rich in hydroxy groups which facilitate the ALD growth process [36][54][55]. In our opinion, all of the above factors contributed to the relatively high EQE of the B4

The preparation temperature influences the physicochemical nature and activity of nanoceria

• Robert A. Yokel,
• Wendel Wohlleben,
• Johannes Georg Keller,
• Matthew L. Hancock,
• Jason M. Unrine,
• D. Allan Butterfield and
• Eric A. Grulke

Beilstein J. Nanotechnol. 2021, 12, 525–540, doi:10.3762/bjnano.12.43

• , attributed to N–O, –COOH, or hydroxy groups; probably COOH and the stretching mode of O–H bonds; and either –CH or C–O–C, respectively [16][49][50] (Figure 4). Due to the citrate coating on the solvothermally synthesized nanoceria, the FTIR spectrum shows additional large peaks at 1535 and 1365 cm−1 (Figure

• with the TGA-induced 5% weight loss of the solvothermally synthesized nanoceria at 125 °C due to outgassing of water, including surface hydroxy groups, suggests that NM-212 was calcined. The solvothermally synthesized nanoceria also exhibited a weight loss of ca. 10% due to its citrate coating. EDS

• combustion temperatures are reached. Nanoceria with surface hydroxy groups, as expected for solvothermally synthesized nanoceria, are chemically reactive at physiological temperatures. Increased temperature results in water loss as two surface hydroxy groups condense, forming water and a Ce–O–Ce surface site

Paper-based triboelectric nanogenerators and their applications: a review

• Jing Han,
• Nuo Xu,
• Yuchen Liang,
• Mei Ding,
• Junyi Zhai,
• Qijun Sun and
• Zhong Lin Wang

Beilstein J. Nanotechnol. 2021, 12, 151–171, doi:10.3762/bjnano.12.12

• , which are limiting factors for the triboelectric performance of TENG devices, Chen et al. tried to introduce a nitro group into the counter cellulose friction layer to change the triboelectric polarity of cellulose with higher electron-attractive capacity [94]. The hydroxy groups in the cellulose

• decreases in a low RH condition. As the RH increases, the hydroxy groups of the first physisorbed layer bond to water molecules, through hydrogen bonding, which also permeate into the interlayers of GO. The gradually absorbed water layer creates a uniform barrier layer for the induction of positive charges

A review on the green and sustainable synthesis of silver nanoparticles and one-dimensional silver nanostructures

• Sina Kaabipour and
• Shohreh Hemmati

Beilstein J. Nanotechnol. 2021, 12, 102–136, doi:10.3762/bjnano.12.9

• respect to reaction conditions. FTIR results show that similar to bacteria, carbonyl, amide, and hydroxy groups corresponding to the cellular protein are responsible for the synthesis and stabilization of AgNPs [178][179]. The less non-pathogenic behavior of fungi and their faster synthesis rate suggest

Unravelling the interfacial interaction in mesoporous SiO₂@nickel phyllosilicate/TiO₂ core–shell nanostructures for photocatalytic activity

• Bridget K. Mutuma,
• Xiluva Mathebula,
• Isaac Nongwe,
• Bonakele P. Mtolo,
• Boitumelo J. Matsoso,
• Rudolph Erasmus,
• Zikhona Tetana and
• Neil J. Coville

Beilstein J. Nanotechnol. 2020, 11, 1834–1846, doi:10.3762/bjnano.11.165

• hydroxy groups bonded to nickel atoms (δ(NiO–H) band) in NiPS as multiple peaks were recorded between 630 and 710 cm−1 [57]. XPS analysis of mSiO2@NiPS and mSiO2@NiPS/TiO2 X-ray photoelectron spectroscopy (XPS) was used to study the surface composition of mSiO2@NiPS and mSiO2@NiPS/TiO2. The complete scans

• three peaks with binding energies of 534.1, 533.2, and 532 eV (Figure 4c). The peaks with lower binding energy correspond to the presence of lattice oxygen bonded to Si, Ni, and/or Ti while the higher binding energy is due to defect oxygen associated with the presence of surface hydroxy groups [56

Cu₂O nanoparticles for the degradation of methyl parathion

• Juan Rizo,
• David Díaz,
• Benito Reyes-Trejo and
• M. Josefina Arellano-Jiménez

Beilstein J. Nanotechnol. 2020, 11, 1546–1555, doi:10.3762/bjnano.11.137

• , abundant, moderately stable, and reliable source of material for the degradation of MP. It is well known that nanoparticles have the advantage of a relatively high surface area. We have used this advantage to increase the basicity of Cu2O in the form of surface hydroxy groups (OH). This also decreased the

• through a nucleophilic substitution at the phosphorous atom (SN2@P), in which hydroxy groups are the nucleophile as Liu et al. have reported [14], and not at aliphatic or aromatic carbon atoms (SN2@C) [14][39]. Furthermore, Cu2O NPs play an important role in the degradation of MP since hydroxy groups are

• found on its surface (see XPS results below). These surface hydroxy groups can either be directly involved in the SN2@P mechanism or they can polarize the oxygen–hydrogen bonds of the water molecules and thus facilitate the hydrolysis of MP. Further research regarding the exact mechanism for the